| MERGERS & ACQUISITIONS |
|---|
| Acquiring Company | Target | Deal Summary |
| Agilent Technologies | Multiplicom, Belgiumbased molecular diagnostics firm spun off from Univ. of Antwerp in 2011 | - Price: €68 million ($70.6 million) in cash
- AT to offer jobs to all 90 M employees
- Lure is M's BRCA Tumor MASTR Plus Dx test, first ovarian cancer companion test to get CE-IVD designation in Europe
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| Menarini-Silicon Biosystems | Janssen Diagnostics | - MSB acquires JD's Cellsearch circulating tumor cell system for monitoring breast, prostate and colorectal cancers
- Cellsearch is only breast cancer monitoring system approved by China FDA
|
| Abbott Laboratories | St. Jude Medical | - European Commission OKs on antitrust grounds provided that: i. SJ divests Angio-Seal and Femoseal vascular closure assets; and ii. A divests Vado steerable sheath
- All latter assets already slated for sale to Japanese firm Terumo for $1 billion
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| Takara Bio USA Holdings | Rubicon Genomics | - Helps T fortify position in pre-analytical genetic sample preparation and expand into in vitro fertilization
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| Grifols | Hologic, Inc.'s blood screening assets | - Price: $1.85 billion cash gross proceeds
- G and H were partners in blood screening business with H doing R&D and manufacturing and G concentrating on commercialization
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| Abbott Laboratories | Alere | - Abbott sues to get out of $5.8 billion acquisition deal inked in Feb. (See LIR, Dec. 2016)
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| DNA Diagnostics Center | Identigene, subsidiary of Sorenson Genomics | - US/UK-based DDC acquires first company to sell in-home DNA paternity test collection kits in US mass retail stores including Rite Aid, CVS and Walmart
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| Boston Scientific | Neovasc | - BS acquires 15% equity stake + N's advanced biological tissue business
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| Takara Bio USA Holdings (subsidiary of Takara Bio USA) | Wafergen Biosystems | - W shareholders approve merger announced in May
- Price: Aggregate cash price based on a multiple of W's 2016 calendar year revenues up— subject to $50 million cap
- T to make two separate $2.5 million deposits in Jan.
|
| STRATEGIC ALLIANCES |
| Partner 1 | Partner 2 | Deal Summary |
| Henry Ford Health System Pathology and Laboratory Medicine | Beckman Coulter Inc. | - Purpose 1: Fully automate HF Hospital lab
- Purpose 2: Modernize equipment at 12 other HF locations
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| Roche | Pacific Biosciences | - R ends 2013 $75 million agreement with PacBio to develop and commercialize diagnostic single-molecule sequencing system, effective Feb. 10, 2017
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| Agilent Genomics (the genomics arm of Agilent Technologies) | Transcriptic (Bay Area diagnostic software firm) | - Incorporates AG mutagenesis and cloning product lines to protocol library within T's robotic cloud laboratory
- Deal covers AG's QuikChange site-directed mutagenesis kits
|
| Novogene | AITbiotech | - Form NovogeneAIT Genomics Singapore, a joint venture to establish a whole-genome sequencing and bioinformatics center in Singapore
- Joint venture will also collaborate with Genome Institute of Singapore in developing use of whole-genome sequencing for cancer diagnosis
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| Royal Phillips | New York Medical College | - Expansion of current partnership to develop IntelliSpace Genomics, an application that provides analysis workflows for pathologists, oncologists and researchers by integrating raw data from multiple sources
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| Evogen | UCB | - Collaboration to develop EvoScore START, a diagnostic test that measures a panel of blood-based protein biomarkers to distinguish between epileptic seizures and other events
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| Courtagen Life Sciences | Certainty Health | - Gives Courtagen exclusive access to CH's mobile device-based data sharing platform for neurological diseases
- Allows Courtagen to import its own neurological disease data into the platform
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| SystemOne | Daktari Diagnostics | - Partnership to improve workflow and identify operational efficiencies for catheterization and electrophysiology labs at UH Cleveland Medical Center
|
| DISTRIBUTION AGREEMENTS |
| Property Owner | Distributor | Deal Summary |
| MDxHealth | AceCGT Life Sciences Limited | - Product: Prostate Cancer test
- Territory: Hong Kong Macao
|
| Dovetail Genomics LLC | Tomy Digital Biology Co. | - Product: Genome assembly services for researchers
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| Illumina Netherlands | GenDx | - Product: Next-generation sequencing instruments and reagents used for HLA sequencing
- Territory: UK, Germany, Italy, Belgium, Netherlands, Luxembourg, Finland
- Non-exclusive reselling rights
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| NantHealth | Oncotest-Teva (subsidiary of Teva Pharmaceuticals) | - Product: GPS Cancer molecular test
- Exclusive reselling rights
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| NantHealth | Lunatus | - Product: GPS Cancer molecular test
- Territory: Middle East, including UAE, Kuwait, Saudi Arabia, Oman, Bahrain, Qatar, Lebanon
- Exclusive reselling rights
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| Argos Technologies | Bibby Scientific | - Products: Molecular and cell biology research products, storage and cryo-storage equipment
- Territories: Europe, Middle East, Africa
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| Kapa Biosystems (owned by Roche) | Merck | - Products: Extends existing distribution alliance to include Kapa's polymerase chain reaction (PCR) and quantitative real-time PCR (qPCR) enzyme products
- Territory: All markets except US, Japan and Brazil
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| Kapa Biosystems (owned by Roche) | MilliporeSigma | - Products: Extends existing distribution agreement to include Kapa's polymerase chain reaction (PCR) and quantitative real-time PCR (qPCR) enzyme products
- Territory: All markets except US, Japan and Brazil
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| Senseonics | Roche | - Product: Eversense, S's long-term implantable continuous glucose monitor
- Territory: Extends current distributorship agreement covering Germany, Italy and the Netherlands to all of Europe (except Scandinavia), the Middle East (except Israel) and Africa
- Exclusive sale, promotion and marketing rights
|
| LICENSES |
| Licensor | Licensee | Deal Summary |
| Thermo Fisher Scientific | Singulex | - Product: TF's BRAHMS PCT procalcitonin immunoassay
- PCT used in US to assess critically ill patients' risks of severe sepsis and septic shock and mortality risks of patients diagnosed with sepsis
- FDA recently approved use of PCT for critically ill patients before admission to the ICU (previously, the patient had to be in the ICU already)
- Non-exclusive: Thermo has also licensed PCT to Roche and Biomérieux
|
| Labcyte | Notable Labs | - Product: L's Echo acoustic liquid handling technology for personalizing drug therapy
- NL will use Echo in its own labs to functionally assess effects of FDA-approved drugs on live primary cancer cells from individual patients
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| Epicentre (a subsidiary of Illumina) | Lucigen | - Products: Array of research products from E's AmpliScribe, CopyControl, MaxPlax and TranforMax product lines
- L to take over manufacture and sale
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| SELLING & MARKETING AGREEMENTS |
| Property Owner | Seller | Deal Summary |
| Good Start Genetics | Roche Diagnostics | - Product: Gene Vu, GSG's screening test to identify carriers of genetic disorders
- R to sell Gene Vu along with its own Harmony prenatal fetal aneuploidy test
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| Edico Genome | Amazon Web Services | - Provides for E's Dragen bioinformatics platform to be sold on new Amazon cloud-based instances
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