PRECISION MEDICINE

Panel Size Affects Accuracy of Tumor Mutational Burden Calculation

Panel size is a critical determinant of test performance and cutoff values for determining the tumor mutational burden (TMB) to guide treatment decisions with immunotherapies, according to a study … [Read more...]

GENETIC TESTING

Sequencing-Based Panel May Improve Evaluation of Thyroid Nodules

A genetic test panel can help patients avoid unnecessary diagnostic thyroid surgeries, according to a study published Nov. 8 in JAMA Oncology. More than six in 10 of patients with thyroid nodules of … [Read more...]

EMERGING TESTS

At-Home, Smartphone-Based Urine Testing Now a Clinical Reality

In what has been called the "era of the medical selfie," at-home, smartphone-based urine testing is now a reality. In a short timeframe, the U.S. Food and Drug Administration (FDA) cleared … [Read more...]

INFORMATICS

AI May Cut ‘Wrong Blood in Tube’ Errors

Machine learning-based multianalyte delta checks may be effective at identifying 'wrong blood in tube' (WBIT) errors, according to a proof-of-concept study published in the American Journal of … [Read more...]

INNOVATION

Liquid Biopsies Enable Pediatric Brain Cancer Monitoring

Liquid biopsies may enable physicians to monitor treatment effectiveness for children with brain cancer, enabling detection of progression earlier than MRI imaging, according to a small study … [Read more...]

EMERGING TESTS

Similar Driver Mutations Seen Across Metastasized Cancer

Driver mutations that are responsible for cancer growth are similar among metastases in a single patient, according to a study published Sept. 7 in Science. Thus, the authors say, a single biopsy is … [Read more...]

EMERGING TESTS

Point-of-Care Test Can Increase Access to Toxoplasma Testing

A novel fingerstick test may improve access to Toxoplasma gondii testing for pregnant women, according to a study published Aug. 16 in PLoS Neglected Tropical Diseases. The study demonstrates that the … [Read more...]

INNOVATION

AI Using Laboratory Data to Inform Clinical Decisions

Artificial intelligence- (AI-) based technology is beginning to penetrate health care. Like most other clinical decision-making, several early AI applications rely upon laboratory data. While … [Read more...]

EMERGING TESTS

Metabolite Panel May ID Kids With Autism Spectrum Disorder

A group of blood metabolites help detect some children with autism spectrum disorder (ASD), according to a study published Sept. 6 in Biological Psychiatry. This panel may indicate alterations in … [Read more...]

EMERGING TESTS

Preimplantation Genetic Testing Improves IVF Outcomes

Preimplantation genetic testing for aneuploidy (PGT-A) can mitigate the negative effects of maternal age on in vitro fertilization (IVF) outcomes by selecting normal embryos that are more likely to … [Read more...]


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