Study Showing PGx Testing Improves Depression Outcomes, Key to Myriad’s Reimbursement Strategy

Pharmacogenomic testing (PGx) provides clinically meaningful improvement in response and remission rates for difficult-to-treat depression patients over standard of care, according to a study … [Read more...]


Diagnostics Sector Saw Increased Investment, Exits in 2018

Life science and health care companies had a banner year in 2018, with a record-breaking year for venture capital investment, according to Silicon Valley Bank's Trends in Healthcare Investments and … [Read more...]


Sequencing Shows Promise in Care of Common Kidney Disease

Exome sequencing can yield a genetic diagnosis in almost 10 percent of patients with chronic kidney disease (CKD), according to a study published Jan. 10 in the New England Journal of Medicine. This … [Read more...]


Cytokines Could Predict Risk of Side Effects From Immunotherapy

Blood-based cytokine markers may help identify cancer patients at greatest risk of developing side effects from immunotherapy treatment, according to a pilot study published Oct. 31 in the British … [Read more...]


Polygenic Risk Score Predicts Drug Efficacy with Schizophrenia

A polygenic risk score (PRS) may be able to predict response to antipsychotic drug treatment in patients with their first episode of psychosis from schizophrenia, according to a study published Nov. 5 … [Read more...]


Panel Size Affects Accuracy of Tumor Mutational Burden Calculation

Panel size is a critical determinant of test performance and cutoff values for determining the tumor mutational burden (TMB) to guide treatment decisions with immunotherapies, according to a study … [Read more...]


Sequencing-Based Panel May Improve Evaluation of Thyroid Nodules

A genetic test panel can help patients avoid unnecessary diagnostic thyroid surgeries, according to a study published Nov. 8 in JAMA Oncology. More than six in 10 of patients with thyroid nodules of … [Read more...]


At-Home, Smartphone-Based Urine Testing Now a Clinical Reality

In what has been called the "era of the medical selfie," at-home, smartphone-based urine testing is now a reality. In a short timeframe, the U.S. Food and Drug Administration (FDA) cleared … [Read more...]


AI May Cut ‘Wrong Blood in Tube’ Errors

Machine learning-based multianalyte delta checks may be effective at identifying 'wrong blood in tube' (WBIT) errors, according to a proof-of-concept study published in the American Journal of … [Read more...]


Liquid Biopsies Enable Pediatric Brain Cancer Monitoring

Liquid biopsies may enable physicians to monitor treatment effectiveness for children with brain cancer, enabling detection of progression earlier than MRI imaging, according to a small study … [Read more...]