Panel size is a critical determinant of test performance and cutoff values for determining the tumor mutational burden (TMB) to guide treatment decisions with immunotherapies, according to a study … [Read more...]
PRECISION MEDICINE
Panel Size Affects Accuracy of Tumor Mutational Burden Calculation
December 17, 2018
GENETIC TESTING
Sequencing-Based Panel May Improve Evaluation of Thyroid Nodules
December 10, 2018
A genetic test panel can help patients avoid unnecessary diagnostic thyroid surgeries, according to a study published Nov. 8 in JAMA Oncology. More than six in 10 of patients with thyroid nodules of … [Read more...]
EMERGING TESTS
At-Home, Smartphone-Based Urine Testing Now a Clinical Reality
December 3, 2018
In what has been called the "era of the medical selfie," at-home, smartphone-based urine testing is now a reality. In a short timeframe, the U.S. Food and Drug Administration (FDA) cleared … [Read more...]
INFORMATICS
AI May Cut ‘Wrong Blood in Tube’ Errors
October 29, 2018
Machine learning-based multianalyte delta checks may be effective at identifying 'wrong blood in tube' (WBIT) errors, according to a proof-of-concept study published in the American Journal of … [Read more...]
INNOVATION
Liquid Biopsies Enable Pediatric Brain Cancer Monitoring
October 29, 2018
Liquid biopsies may enable physicians to monitor treatment effectiveness for children with brain cancer, enabling detection of progression earlier than MRI imaging, according to a small study … [Read more...]
EMERGING TESTS
Similar Driver Mutations Seen Across Metastasized Cancer
October 29, 2018
Driver mutations that are responsible for cancer growth are similar among metastases in a single patient, according to a study published Sept. 7 in Science. Thus, the authors say, a single biopsy is … [Read more...]
EMERGING TESTS
Point-of-Care Test Can Increase Access to Toxoplasma Testing
October 22, 2018
A novel fingerstick test may improve access to Toxoplasma gondii testing for pregnant women, according to a study published Aug. 16 in PLoS Neglected Tropical Diseases. The study demonstrates that the … [Read more...]
INNOVATION
AI Using Laboratory Data to Inform Clinical Decisions
October 15, 2018
Artificial intelligence- (AI-) based technology is beginning to penetrate health care. Like most other clinical decision-making, several early AI applications rely upon laboratory data. While … [Read more...]
EMERGING TESTS
Metabolite Panel May ID Kids With Autism Spectrum Disorder
October 9, 2018
A group of blood metabolites help detect some children with autism spectrum disorder (ASD), according to a study published Sept. 6 in Biological Psychiatry. This panel may indicate alterations in … [Read more...]
EMERGING TESTS
Preimplantation Genetic Testing Improves IVF Outcomes
September 24, 2018
Preimplantation genetic testing for aneuploidy (PGT-A) can mitigate the negative effects of maternal age on in vitro fertilization (IVF) outcomes by selecting normal embryos that are more likely to … [Read more...]
