Incomplete implementation of EGFR testing guidelines remains a problem in the realm of non-small cell lung cancer (NSCLC), according to a study published in the Journal of Global Oncology. The authors … [Read more...]
PRECISION MEDICINE
Can a Blood Test Quantify Pain?
April 15, 2019
A new test could help clinicians objectively measure pain. According to a study published Feb. 12 in Molecular Psychiatry, the identified biomarkers can predict pain severity and future emergency … [Read more...]
GENETIC TESTING
ASCO Endorses CAP’s Practice Guidelines for HPV Testing in Head, Neck Cancers
April 1, 2019
The American Society of Clinical Oncology endorsed the American Pathologists' practice guidelines for human papillomavirus (HPV) testing in head and neck cancers. The guidelines recommend that HPV … [Read more...]
PRECISION MEDICINE
Exome Sequencing Improves Diagnosis of Fetal Structural Anomalies
March 15, 2019
Prenatal diagnostics have evolved from conventional cytogenetic analysis to increasingly chromosomal microarray analysis, within the last 10 years. While whole-exome sequencing (WES) has shown utility … [Read more...]
PRECISION MEDICINE
Donor-Derived, Cell-Free DNA May Predict Lung Transplant Rejection
March 11, 2019
Elevated donor-derived, cell-free DNA (ddcfDNA) in the 3 months post-lung transplant can identify clinically silent allograft injury and predict progression to chronic rejection, according to a … [Read more...]
EMERGING TESTS
Calprotectin May Predict Arthritis Relapse
February 25, 2019
Baseline calprotectin serum levels independently predicted disease relapse in patients with rheumatoid arthritis (RA) and psoriatic arthritis (PsA) taking tumor necrosis factor inhibitors (TNFi) … [Read more...]
TOP OF THE NEWS
Genetic Risk of Prostate Cancer Underestimated; Testing Guidelines Miss Men With Elevated Prostate Cancer Risk
February 25, 2019
Neither guideline eligibility nor Gleason scores are reliable for predicting prostate cancer risk due to pathogenic germline variants, according to a study published Feb. 7 in JAMA Oncology. The … [Read more...]
TESTING STRATEGY
New Studies Question Utility of Gene Expression Testing for Cancers With Unknown Primary Site, Low-Risk Breast Cancer
February 25, 2019
Gene expression profiling has been making inroads into clinical cancer care, with application in cancer classification, most notably with breast cancer. Two recent studies are calling into question … [Read more...]
EMERGING TESTS
Study Showing PGx Testing Improves Depression Outcomes, Key to Myriad’s Reimbursement Strategy
February 18, 2019
Pharmacogenomic testing (PGx) provides clinically meaningful improvement in response and remission rates for difficult-to-treat depression patients over standard of care, according to a study … [Read more...]
INDUSTRY TRENDS
Diagnostics Sector Saw Increased Investment, Exits in 2018
January 28, 2019
Life science and health care companies had a banner year in 2018, with a record-breaking year for venture capital investment, according to Silicon Valley Bank's Trends in Healthcare Investments and … [Read more...]
